Sarcomatoid Mesothelioma Histology
Sarcomatoid mesothelioma is the least common cell type of mesothelioma and known for its abnormal spindle shape.
Sarcomatoid mesothelioma histology. Consequently there are many diseases to be differentiated when the diagnosis of mesothelioma is based on histological analyses. It can occur in the linings of the lungs abdomen and heart. Mesothelioma is classified into four main types based on the part of the body. Sarcomatoid cells are sometimes hard to recognize as they can appear very similar to normal healthy cells.
Histopathology falls within the larger field of pathology. I pleural mesothelioma is a cancer that develops in tissue surrounding the lungs ii pericardium mesothelioma originates in the pericardium membrane lining the heart iii peritoneal mesothelioma starts growing around the abdominal organs and iv tunica vaginalis mesothelioma is a cancer that forms on the membrane lining the testicles. Sarcomatoid mesothelioma is a more treatment resistant type of mesothelioma. However immunohistochemical analyses of sarcomatoid mesothelioma the less common type are limited and its distinction from other tumors of the chest wall lung and pleura is often problematic.
Sometimes referred to as spindle cell mesothelioma sarcomatoid cells are recognized by their oval spindle shape. It can take many forms. It accounts for approximately 10 20 of all mesothelioma diagnoses. Histopathology is the study of diseased cells.
This cell type comprises around 20 of cases involving pleural mesothelioma. Sarcomatoid mesothelioma is the rarest of the mesothelioma cell types accounting for between 10 and 20 of all mesothelioma cases. The immunohistochemical characteristics of epithelioid malignant mesothelioma are well described. Pathologists recognize sarcomatous mesothelioma cells by their long spindle like shape.
Mesothelioma can be categorized histologically as epithelioid type sarcomatoid type biphasic type desmoplastic type among others. Chemotherapy and radiation are the most common treatment options. Sarcomatous cells spread quickly and make up about 10 to 20 of all mesothelioma cases. Sarcomatoid mesothelioma is a rare cell type caused by asbestos exposure.
Understanding sarcomatoid cell type. Sarcomatoid cell type is extremely rare for peritoneal mesothelioma. Defining characteristics of sarcomatoid mesothelioma cells when determining what type of mesothelioma a patient has physicians will use histology the study of cells to analyze tumor cells and differentiate type.