Leukemia Cutis Skin Lesions
This condition may be contrasted with leukemids which are skin lesions that occur with leukemia but which are not related to leukemic cell infiltration.
Leukemia cutis skin lesions. Bleeding from the gums bone and joint pain fever frequent infections frequent or severe nosebleeds lumps caused by swollen lymph nodes in and around the neck underarm abdomen or groin pale. Leukaemia cutis can present with various types of skin lesion. Leukemia cutis is the infiltration of neoplastic leukocytes or their precursors into the skin resulting in clinically identifiable cutaneous lesions. Only about 3 percent of those with leukemia will experience leukemia cutis.
That is they are not itchy or sore. Acute leukemias are due to malignant transformation of leukocytes early in development while chronic leukemias arise from more differentiated malignant leukocytes. Most skin complications of leukemia are leukemids lesions that are unrelated to leukemic infiltration of the skin. The term leukemia cutis lc describes the skin changes caused by infiltration of extramedullary leukemic cells.
Leukemia cutis is the infiltration of neoplastic leukocytes or their precursors into the epidermis the dermis or the subcutis resulting in clinically identifiable cutaneous lesions. Firm papules small bumps nodules larger lumps and plaques thickened flat patches which may be skin coloured red brown or purple diffuse eczema like red dry thickened skin erythroderma. While the skin is the third most common place for leukemic involvement after the blood and bone marrow leukemia cutis is a rare condition.