Creatine Kinase Reference Range Uk

This test is used to investigate cardiac or skeletal muscle pathology. This test measures the amount of creatine kinase ck in the blood. Other tissues such as kidney have low levels of enzyme activity.

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Creatine kinase reference range uk. 32 294 u l. 33 211 u l. Reference ranges are dependent on. We are not a laboratory and are unable to comment on an individual s health and treatment.

Lab tests online uk is an educational website designed to provide patients and carers with information on laboratory tests used in medical care. The investigation of musculo skeletal diseases such as muscular dystrophy. Creatine kinase ck is found in cardiac and skeletal muscle and brain. Creatine kinase ckmb creatinine creatinine clearance cryoglobulin cryoprecipitate.

Ck is found predominantly in the heart muscle skeletal muscle and brain and are elevated when these muscle or nerve cells are injured. Ck rises approximately 6 hours after myocardial infarction mi and may remain elevated for 36 48 hours. The highest creatine kinase on record was over a million and was caused solely by a heavy workout. 7100 15900 umol 24hrs female.

They can rise within 6 hours after damage and if damage does not continue the levels peak at 18 hours after injury and return to normal in 2 to 3 days. For health information and advice visit nhs uk. A study of over 700 athletes suggests that normal reference ranges for athletes may be over two times higher than normal ranges. 50 120 umol l urine male.

Creatine kinase ck is a dimeric enzyme that catalyses the reversible phosphorylation of creatine by atp. The ck enzyme is a dimer composed of subunits derived from. Ck is a type of protein known as an enzyme. Skeletal muscles are the muscles attached to your skeleton.

82 1 083 u l in men and 47 513 u l in women. Ck is released into blood following damage to muscle tissue resulting in elevated serum plasma ck activity. 5200 14100 umol 24hrs. Mft nhs uk laboratorymedicine 2 2 biological reference range or cut off.

Physiologically when muscle contracts atp is converted to adenosine diphosphate adp and ck catalyzes the rephosphorylation of adp to atp using creatine phosphate as the phosphorylation reservoir. What is a creatine kinase ck test. It is mostly found in your skeletal muscles and heart with lesser amounts in the brain. Serum or lithium heparin plasma.

Creatine kinase ck is an enzyme that catalyzes the reversible phosphorylation of creatine cr by adenosine triphosphate atp.