Congenital Myasthenia Gravis Symptoms

These symptoms often result in double vision and difficulty chewing and swallowing.

Congenital myasthenia gravis symptoms. The most common symptoms of cms include. Facial muscles including muscles that control the eyelids muscles that move the eyes and muscles used for chewing and swallowing are most commonly affected. Congenital myasthenia gravis cmg is a form of weakness most likely presenting itself during infancy with fatigability difficulty sucking on pacifier inactivity and decreased tone of the muscles. Congenital myasthenic syndromes may affect your nerve cells presynaptic your muscle cells postsynaptic or the space between your nerve and muscle.

When to see a doctor. This is referred to as fatigable weakness. Weakness in your legs can. Your speech might sound soft or nasal depending on which muscles have been.

Depending on the type symptoms of cms vary from mild to severe but generally include weakness fatigue and ptosis droopy eyelids. In other cases weakness is stable and does not worsen over time. Presynaptic symptoms include brief stops in breathing weakness of the eye mouth and throat muscles. If a child has difficulty breathing feeding or swallowing they may be vulnerable to pneumonia or respiratory failure.

Postsynaptic symptoms in infants include severe muscle weakness feeding and respiratory problems and delays in the ability to sit crawl and walk. Congenital myasthenic syndromes are rare hereditary genetic conditions resulting from a defect at the junction where your nerve stimulates muscle activity. The earlier the onset of cms the more severe the symptoms are likely to be. Face and throat muscles.

All subtypes involve muscle fatigue and weakness that usually begins at an early age. That defect causes muscle weakness. The muscle weakness typically begins in early childhood but can also appear in adolescence or adulthood. The prognosis depends on the specific subtype of congenital myasthenia the muscles involved and the age at onset of symptoms.

Muscle weakness that is brought on by activity or exercise. Symptoms of congenital myasthenia gravis. The symptoms of the congenital myasthenic syndromes cms vary by the age at which symptoms begin type of muscle weakness and severity. Signs symptoms the cardinal symptom of all myasthenic disorders is muscle weakness that is induced or worsened by exertion.

The list of signs and symptoms mentioned in various sources for congenital myasthenia gravis includes the 14 symptoms listed below. Congenital myasthenic syndrome is a group of conditions characterized by muscle weakness myasthenia that worsens with physical exertion.